We’re now officially past the first set of College Football Playoff rankings, leading to rising stakes, vanishing excuses, and shrinking rooms for error. Week 11 doesn’t play favorites, but it instead simply spreads the chaos evenly across every conference, making sure no fan base escapes without mild heartburn or existential dread. The action begins Friday night as Northwestern visits 19th-ranked USC in a B1G time capsule no one saw coming, while Tulane’s trip to Memphis quietly carries massive stakes towards the Group of Five’s CFP bid. Saturday, however, delivers the real avalanche, headlined by a top-10 Big XII showdown between unbeaten BYU and one-loss Texas Tech that could redefine the playoff conversation. Elsewhere, Alabama hosts LSU in their annual grudge match of pride and stubbornness, although the matchup isn’t as exciting as advertised from the start of the season due to LSU’s struggles and Brian Kelly’s recent firing, Georgia visits Mississippi State in a potential trap game that could shake things up fast at the top of the SEC standings, and Texas A&M tries to keep its perfect season alive against a ranked Missouri team that will be without it’s leader under center. Every league has something on the line, and every contender has something to lose, because November never lets anyone breathe easy. With that in mind, let’s take a look at some of the weekend’s most exciting matchups to watch:

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Friday, November 7

Northwestern @ #19 USC (-14.5) (O/U: 52.5)

Los Angeles Memorial Coliseum, Los Angeles, CA

9 pm, FOX

Best Bet: Under 52.5

Prediction

Final Score: #19 USC 28, Northwestern 13

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Tulane @ Memphis (-3.5) (O/U: 53.5)

Simmons Bank Liberty Stadium, Memphis, TN

9 pm, ESPN

Best Bet: Greg Desrosiers Anytime TD

Prediction

Final Score: Memphis 34, Tulane 27

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Saturday, November 8

#7 BYU @ #8 Texas Tech (-10.5) (O/U: 51.5)

Jones AT&T Stadium, Lubbock, TX

Noon, ABC

Best Bet: BYU +10.5

Prediction

Final Score: #8 Texas Tech 31, #7 BYU 24

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#2 Indiana (-14.5) @ Penn State (O/U: 50.5)

Beaver Stadium, University Park, PA

Noon, FOX

Best Bet: Indiana -14.5

Prediction

Final Score: #2 Indiana 45, Penn State 14

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#5 Georgia (-9.5) @ Mississippi State (O/U: 56.5)

Davis Wade Stadium, Starkville, MS

Noon, ESPN

Best Bet: Anthony Evans o60.5 Receiving Yards

Prediction

Final Score: #5 Georgia 31, Mississippi State 28

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#3 Texas A&M (-6.5) @ #22 Missouri (O/U: 48.5)

Faurot Field at Memorial Stadium, Columbia, MO

3:30 pm, ABC

Best Bet: Matt Zollers o182.5 Passing Yards

Prediction

Final Score: #3 Texas A&M 27, #22 Missouri 21

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#9 Oregon (-6.5) @ #20 Iowa (O/U: 42.5)

Kinnick Stadium, Iowa City, IA

3:30 pm, FOX

Best Bet: Iowa +6.5

Prediction

Final Score: #20 Iowa 23, #9 Oregon 17

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Kansas @ Arizona (-5.5) (O/U: 57.5)

Arizona Stadium, Tucson, AZ

3:30 pm, ESPN2

Best Bet: Leshon Williams o39.5 Rushing Yards

Prediction

Final Score: Kansas 38, Arizona 27

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Wake Forest @ #14 Virginia (-6.5) (O/U: 47.5)

Scott Stadium, Charlottesville, VA

7 pm, ESPN

Best Bet: Over 47.5

Prediction

Final Score: #14 Virginia 30, Wake Forest 23

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LSU @ #4 Alabama (-10.5) (O/U: 49.5)

Bryant-Denny Stadium, Tuscaloosa, AL

7:30 pm, ABC

Best Bet: Aaron Anderson o35.5 Receiving Yards

Prediction

Final Score: #4 Alabama 27, LSU 17

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Stay tuned this weekend for yet another stacked weekend of college football!