Week 3 of the 2025 college football season arrives with a slate that feels both revealing and unforgiving, as several top-25 clashes carry postseason weight while rivalries and storylines deepen the drama, and nowhere is that more evident than in Knoxville, where a surging #15 Tennessee squad eager to prove it belongs back among the SEC’s best against an elite sixth-ranked Georgia Bulldog defense. In South Florida, #18 USF meets #5 Miami in a battle that not only tests the Hurricanes’ offensive firepower but also gives the Bulls a chance to validate their climb into the national spotlight, while in South Bend, #16 Texas A&M travels north to confront #8 Notre Dame in a contest that could hinge on line-of-scrimmage play and quarterback efficiency. Beyond the marquee pairings, #12 Clemson’s road trip to Georgia Tech carries ACC title race implications, the Backyard Brawl renews one of the sport’s most heated rivalries, Darian Mensah returns to Tulane in Duke blue for an emotional reunion, and #3 LSU hosts Florida under the lights in Death Valley, where the Gators will be tested in an extremely hostile SEC setting following their embarrassment from a week ago to USF.

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Saturday, September 13

Wisconsin @ #19 Alabama (-20.5) (O/U: 44.5)

Bryant-Denny Stadium, Tuscaloosa, AL

Noon, ABC

Wisconsin makes the trip to Tuscaloosa with hopes of proving that Luke Fickell’s second season will not mirror the rocky debut that produced the program’s first season-opening loss in more than two decades, yet the Badgers face a steep climb against an Alabama team eager to take out its frustration after falling to Florida State just two weeks ago. While new offensive coordinator Jeff Grimes has injected a different look into the system and former San Diego State quarterback Danny O’Neil has impressed with poise and accuracy through two games, questions remain about how effectively the young quarterback can handle consistent pressure, particularly behind a line already adjusting to previous injuries. The running game, once Wisconsin’s calling card, is still searching for a breakout performer, especially after Tawee Walker left, and that makes sustained drives against linebackers like Deontae Lawson and Justin Jefferson as well as an opportunistic Crimson Tide secondary led by Domani Jackson and Dre Kirkpatrick Jr. a daunting task. On defense, Christian Alliegro and Tackett Curtis bring experience and toughness, but slowing down Ty Simpson, Ryan Williams, and Germie Bernard as they try and stretch the field will require more than flashes of disruption. Alabama, retooled under Kalen DeBoer and playing with an edge after last year’s stumble, will look to control the trenches on both sides and turn this matchup into a statement, while Wisconsin’s aim is to show it can stand firmer than in last season’s lopsided loss and leave with a clearer sense of progress.

Best Bet: Ty Simpson o1.5 Passing TDs

The most intriguing angle heading into this matchup centers around Ty Simpson, whose performance through the first two weeks has been heavily relied on with Jam Miller out in the running back room, and considering that he only needs to throw two touchdown passes, I feel really confident he’ll cover that line. Simpson looked somewhat uneven in the opener against Florida State, completing just over half of his throws but still managing to deliver two scoring strikes without a turnover, and then followed that effort by dismantling UL Monroe in surgical fashion, going 17-for-17 with three touchdowns in a flawless display that reminded everyone why Nick Saban and his staff trust him to lead an offense loaded with talent. Now, facing a Wisconsin defense that no longer has stalwarts like Hunter Wohler and Xavier Lucas in the secondary, Simpson will have every opportunity to exploit mismatches with his chemistry-rich targets Bernard and Williams, especially since they want to get off to a quick start early. For Alabama, this game represents a chance to channel the frustration from their Week 1 loss and prove they can overwhelm another Power Four opponent, while Wisconsin is determined to keep things competitive after last year’s 42-10 blowout in Madison. Yet with Simpson’s efficiency, his ability to stretch the field, and his knack for finishing drives in the red zone, the stage is set for him to air out at least two touchdowns and tilt the contest in Alabama’s favor once again.

Prediction

This feels like the kind of afternoon where Alabama seizes control early and refuses to let go, using the game as both a statement and a tune-up before a much-needed bye week and the looming showdown with Georgia in Athens. Kalen DeBoer’s group learned some hard truths against Florida State, but considering the Seminoles are a legitimate CFP contender, there’s little reason for Alabama to hang their heads, and the Tide now look primed to unleash their full arsenal on a Wisconsin team that simply doesn’t have the depth or explosiveness to keep pace. Expect Simpson to come out firing early, connecting on plenty of deep throws to quickly establish rhythm through the air while they try and get as much out of their running back depth and ground game in the second half to wear down a Badger front that will be on its heels from the start. Wisconsin will try to slow things down offensively, but once Alabama’s defensive line asserts itself and the Tide build a multi-score cushion, the Badgers’ offense doesn’t have the firepower to chase points. By the second half, the game may feel more like an audition for younger Tide contributors than a true contest, with Alabama piling on production while keeping players fresh for what’s ahead.

Final Score: #19 Alabama 38, Wisconsin 10

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#12 Clemson (-2.5) @ Georgia Tech (O/U: 51.5)

Bobby Dodd Stadium, Atlanta, GA

Noon, ESPN

For the first time in over a decade, Georgia Tech has a genuine opportunity to take down Clemson, and the atmosphere at Bobby Dodd Stadium should reflect the weight of that chance. Brent Key’s program has steadily built toward this type of moment, and after back-to-back winning seasons capped by competitive battles against Georgia, the Yellow Jackets look like a team ready to step into the ACC’s upper tier. Meanwhile, Clemson enters this matchup carrying the expectations that come with being the reigning conference champion, but their early struggles against LSU and Troy exposed lingering inconsistencies that go beyond just minor rust. Cade Klubnik remains one of the nation’s most talented quarterbacks, and he is surrounded by a deep group of receivers, yet the offensive execution has come in uneven spurts, and the running game is still finding its identity without Phil Mafah. Defensively, Tom Allen’s arrival has brought more aggression, particularly up front, but the Tigers have looked vulnerable against physical rushing attacks, a weakness that aligns directly with Georgia Tech’s biggest strength. With Haynes King returning and Jamal Haynes continuing to thrive behind an athletic offensive line, the Jackets enter this game with both the balance and confidence to finally close the gap on a rival that has dominated them since 2014.

Best Bet: Georgia Tech ML

I love Clemson, but I don’t see them winning this game whatsoever with the motivation and hype going around Atlanta. Their sluggish start against Troy highlighted how fragile their rhythm can be, particularly when their ground game stalls, and Georgia Tech is built to make them uncomfortable, and with Jamal Haynes and Malachi Hosley already averaging over six yards per carry, and Haynes King adding another layer of mobility, the Jackets can control tempo while still being explosive enough to stretch the field with Malik Rutherford and Eric Rivers. Clemson’s defense is loaded with talent, but the secondary has shown cracks when left on the field too long, and if Georgia Tech’s offensive line holds its ground, they will have opportunities to capitalize on big plays downfield. On the other side, Klubnik has been turnover-prone, and Georgia Tech’s opportunistic defense has been thriving on creating negative plays, recording double-digit tackles for loss in back-to-back weeks. Add in the home-field energy of Atlanta for a noon kickoff, and the circumstances point toward Georgia Tech delivering a signature win, making the Jackets outright the sharp side here.

Prediction

This matchup sets up as a classic ACC slugfest, but one where Georgia Tech has the tools to dictate terms and prevent Clemson from ever truly settling into its preferred rhythm, especially with Antonio Williams set to miss a second straight game. The Tigers will try to start fast with Klubnik distributing to his deep receiver corps, yet Georgia Tech’s defensive front has shown the discipline and physicality to limit early momentum, forcing Clemson to settle for field goals rather than touchdowns. Once the Jackets’ rushing attack begins to wear down the Tiger front seven, the game script flips in their favor, with Haynes King finding opportunities to push the ball vertically on play-action. Clemson’s defense is strong enough to create a few disruptive moments, but the balance of Georgia Tech’s offense, combined with King’s ability to extend plays, keeps the Yellow Jackets ahead on the scoreboard. By the second half, the Jackets are in control of both tempo and field position, grinding away with sustained drives that chew up clock while keeping the Tigers’ offense on the sideline. Clemson will try to land a few punches late, but Georgia Tech’s motivation, composure, and efficiency allow them to maintain separation, and the Jackets finish the afternoon with their most significant win under Brent Key, positioning themselves as a legitimate ACC contender for the first time in 11 years.

Final Score: Georgia Tech 27, #12 Clemson 17

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Pittsburgh (-7.5) @ West Virginia (O/U: 55.5)

Milan Puskar Stadium, Morgantown, WV

3:30 pm, ESPN

The Backyard Brawl doesn’t need much extra fuel to carry intensity, but this year’s edition feels especially important given that it will be the last meeting on the schedule for the foreseeable future. Pittsburgh enters Morgantown searching for a stabilizing performance, and the matchup sets up well for Pat Narduzzi’s group to make a statement on both sides of the ball. The Panthers have started strong in 2025 with comfortable wins, leaning on quarterback Eli Holstein to spread the field and keep defenses on their heels, while Desmond Reid has provided balance as a runner and receiver. West Virginia, meanwhile, is dealing with a transition period under Rich Rodriguez. Nicco Marchiol has shown flashes of efficiency through two games, but the Mountaineers’ offense is still trying to find consistency without Jahiem White and behind a rebuilt offensive line. That combination puts pressure on a defense still adjusting to a new system under Zac Alley, and against Pitt’s array of skill players, lapses in communication could become costly. Rivalry games tend to bring out wild swings and emotional shifts, but the talent and stability Pitt brings to the table makes this feel more like an opportunity for them to remind the ACC that they’re still a dangerous, balanced team.

Best Bet: Eli Holstein o274.5 Passing Yards

There weren’t very many lines that I liked in this game, as the point spread and game total are both pretty tight for me, and there aren’t very many player props that I liked either. With that being said, I’m just going to shine the spotlight on one of the best players in this game in Eli Holstein, who will shine again and throw a lot in this matchup against a weak West Virginia defense. The Mountaineers were picked apart at times in its first two games, and without proven depth at corner and safety, Holstein’s arm strength and chemistry with Kenny Johnson and Raphael Williams Jr. make explosive gains likely. What also makes this prop attractive is the game flow. West Virginia’s offense doesn’t project to sustain many long drives against Pitt’s defensive front, which means the Panthers will get extra possessions and opportunities to throw. Holstein is also coming off a year where injuries cut short what could have been a breakout season, and there’s a clear sense from the play-calling that Kade Bell wants to give him every chance to rack up numbers early in the year. Even if the game tilts in Pittsburgh’s favor by the second half, the likelihood of Holstein surpassing this total remains high, as the staff will want to keep him sharp  with ACC competition coming up very soon.

Prediction

The last time Rich Rodriguez coached this rivalry game for the Mountaineers, the program was in a much different place, as they were living in the magnificent days of Pat White and hovering around the top of the polls, but Pittsburgh actually won the game. This time around, Holstein and the passing game will put immediate pressure on West Virginia’s defense, forcing the Mountaineers to play from behind. That’s not an ideal position for a roster that has lost offensive rhythm with Jahiem White sidelined and still lacks proven receiving depth. Marchiol will manufacture a few plays with his legs and find Cam Vaughn or Grayson Barnes to keep drives alive, but sustaining that success against Pitt’s aggressive linebackers and deep defensive line rotation will be a steep challenge. As the game wears on, the Panthers’ linebackers should be all over the field, bottle up West Virginia’s rushing attempts, and create turnovers, giving their offense short fields and chances to extend the margin. The Mountaineers will rely on crowd energy to stay within striking distance, but over four quarters the Panthers’ superior balance, experience, and ability to finish drives in the red zone should create a steady separation. I’m expecting a higher scoring game than that 2007 matchup, and I’m also a similar outcome with the Panthers coming out on top.

Final Score: Pittsburgh 30, West Virginia 23

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#6 Georgia (-3.5) @ #15 Tennessee (O/U: 50.5)

Neyland Stadium, Knoxville, TN

3:30 pm, ABC

Georgia has owned this rivalry series against Tennessee for the past eight meetings between these two programs, and entering 2025, it’s clear both teams are poised to make statements early in the season. The Bulldogs are transitioning to Gunner Stockton at quarterback after Carson Beck’s departure, and Stockton has already shown impressive efficiency through the air in wins over Marshall and Austin, completing 67.6% of his passes for nearly 500 yards and three touchdowns without an interception. Complementing the passing attack, Georgia’s rushing game is led by Nate Frazier, who has averaged 4.6 yards per carry, alongside Dwight Phillips Jr. and Chauncey Bowens, providing a multifaceted attack that can punish defenses on the ground. Wide receivers Zachariah Branch and Noah Thomas have stepped into immediate roles alongside Dillon Bell and Colbie Young, maintaining the team’s explosive vertical and intermediate passing threats, while tight ends Oscar Delp and Lawson Luckie provide reliable options both in the passing game and as blockers. Defensively, Glenn Schumann’s unit remains loaded with talent despite first-round departures, with CJ Allen, Raylen Wilson, and KJ Bolden anchoring a front seven and a secondary capable of limiting big plays. Tennessee, meanwhile, is integrating Joey Aguilar at quarterback and a young receiving corps led by Chris Brazzell II and Mike Matthews, and while the Vols have flashed scoring potential in early games, Georgia’s balance, depth, and disciplined execution on both sides of the ball give them a clear edge, making them the favorites to maintain control in this SEC rivalry.

Best Bet: Under 50.5

The Tennessee offense has shown flashes of efficiency early in the season, with Aguilar connecting on big plays to his receiving corps and backs, giving fans reason to be optimistic about the Vols’ ability to move the ball. Aguilar has demonstrated poise and accuracy, completing over 67% of his passes and accounting for multiple touchdowns through two games, and the receivers have made the most of his arm, producing explosive gains in open space. However, while this early offensive explosion has been eye-catching, Tennessee has yet to face a defensive front with the discipline, depth, and talent of Georgia’s unit. The Bulldogs’ defensive line is capable of controlling the line of scrimmage, generating pressure without heavy blitzing, and forcing third-and-long situations that can stall drives and limit big plays. Georgia’s secondary, in addition to their front, is more than equipped to cover Tennessee’s young receivers and tight ends, while the Bulldogs’ ability to run the ball effectively ensures they can manage the clock and control the tempo. Considering Georgia’s track record in recent seasons and the trend of lower scoring in this matchup, it’s reasonable to expect that the total points won’t exceed 50, with methodical drives, key defensive stops, and controlled pace will hold Tennessee’s offensive explosion in check.

Prediction

All week long, I believed Tennessee could finally pull off the upset over Georgia for the first time since their miraculous Hail Mary finish in 2016, but the more I saw people betting on the Vols to pull it off, the more convinced I became that Georgia would keep its streak alive in this storied rivalry. The Bulldogs have the depth, experience, and balance to take over this game, from a versatile rushing attack that can control the pace of this game to a receiving corps capable of stretching the field with big plays down the field if they find themselves down late. On defense, Georgia’s front seven and secondary are adept at generating pressure, defending the deep ball, and forcing third-and-long situations, putting constant stress on Aguilar and his young receivers. Tennessee will certainly have moments of promise, with explosive runs, intermediate completions, or a big defensive play keeping the crowd and scoreboard engaged. However, Georgia’s methodical execution, ability to win key third-downs, and composure under pressure should allow them to dictate the tempo and maintain control possession after possession. This game is likely to come down to the final drive, with the Dawgs capitalizing on critical opportunities late, leaving Tennessee still searching for answers while Georgia solidifies its status as one of the SEC’s elite programs as the season progresses.

Final Score: #6 Georgia 23, #15 Tennessee 21

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#18 USF @ #5 Miami (-17.5) (O/U: 56.5)

Hard Rock Stadium, Miami Gardens, FL

4:30 pm, The CW Network

USF has been a team on a mission lately, taking down two top-25 teams in a row and climbing into the top-25 rankings themselves. However, even with all that success, they still have Miami in front of them, but they’re more than capable of giving them a run for their money, even with how talented the Hurricanes are. Quarterback Byrum Brown has been the catalyst of this rise, showing the kind of poise and versatility that allows Alex Golesh’s offense to thrive in clutch moments, while his growing connection with Keshawn Singleton has turned into one of the most dangerous big-play threats in college football. Their running game hasn’t always been explosive, but it’s been steady enough to balance the offense and keep defenses honest, while their defense has played bend-but-don’t-break football, delivering key stops in the red zone and making momentum-shifting plays when needed. Still, Miami represents a different beast, one with depth across both lines, a battle-tested quarterback in Carson Beck, and enough firepower to stress a defense for four full quarters. The Hurricanes already knocked off Notre Dame in a statement performance and then handled business with ease against Bethune-Cookman, showing they’re capable of handling both marquee showdowns and tune-up contests. For USF, this is an opportunity to prove they belong in the same conversation as programs with legitimate playoff aspirations, and they hope to cap off these first few games with one of the best starts a Group of Five program has had in a long time.

Best Bet: Miami -17.5

Even with how amazing USF has looked, I think this spread is a trap and one that will make bettors want to flood toward the Bulls, making Miami’s chances to cover stronger than people think. They did beat a talented Florida team, but the Gators were in a lookahead spot, and this Miami team is better, more experienced, and more battle-tested so far than the Gators. Behind Mark Fletcher Jr.’s punishing rushing style and Carson Beck’s command of the passing game, the Hurricanes bring more balance and consistency than anything USF has faced in their first two wins. Beck has quickly built a rhythm with CJ Daniels and a deep receiving corps, giving Miami multiple options in the red zone and enough variety to keep a defense guessing on third downs. Meanwhile, Reuben Bain Jr. and the Miami front are exactly the type of disruptive force that can break up the improvisational rhythm of a quarterback like Brown, forcing hurried throws and preventing the Bulls from sustaining long drives. The line might look generous to the underdog given USF’s recent momentum, but the Hurricanes’ roster depth, home-field advantage, and ability to punish mistakes tilt this matchup sharply in their favor. Look into taking Miami to win by at least 18 or more, as USF’s magical run is more than likely to run out of gas.

Prediction

This Miami team is not one to take lightly by any means, and I think they take this game a lot more seriously than USF’s previous opponents. The Hurricanes know exactly what’s at stake with a playoff bid in reach, and Mario Cristobal’s group has shown an ability to stay focused regardless of the opponent. Expect Miami to come out firing, leaning on Beck’s precision passing to grab control early while Fletcher and the ground game wear down the Bulls’ front as the night goes on. USF will almost certainly land a few punches, as Brown’s dual-threat ability can create highlight moments and their defense has a knack for timely stops, but sustaining that for four quarters against this level of competition is a different challenge altogether. As the game moves into the second half, Miami’s depth will become more apparent, particularly on defense where fresh rotations should slow Brown’s rhythm and force the Bulls into more predictable situations. The final score might not be a complete runaway, but the Hurricanes’ efficiency on offense and ability to dictate tempo will keep them comfortably ahead, and by the time the fourth quarter winds down, Miami will have secured another statement win. USF will still leave with respect no matter what happens this weekend, but Miami will leave with momentum and confidence before Florida arrives and their ACC slate begins.

Final Score: #5 Miami 34, #18 USF 13

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Florida @ #3 LSU (-6.5) (O/U: 47.5)

Tiger Stadium, Baton Rouge, LA

7:30 pm, ABC

LSU finally gets their first look at a true marquee night game in Death Valley under the lights, and even though Florida showed us last week that they weren’t as improved as many thought they would be following their heartbreaking loss to USF, this team still has the talent and the mindset that they need to remain alive with as tough of a schedule as they have. What makes this matchup so intriguing is that both programs are in the middle of a defining stretch, and the atmosphere in Baton Rouge should be nothing short of electric, as LSU fans have been waiting for this kind of primetime stage to show whether their team can separate from the pack in the SEC. Florida comes in trying to shake off the inconsistency that has plagued them since the start of the season, but with a roster that still has plenty of four- and five-star players, they remain a dangerous threat if LSU doesn’t play clean football. The crowd noise, the speed of LSU’s defense, and the potential for explosive plays in the passing game will all be key factors, but Florida’s ability to withstand those early punches and respond with long drives will determine if this one becomes a four-quarter battle or tilts heavily toward the Tigers.

Best Bet: Caden Durham Anytime TD

Caden Durham is a name that some might know, but he his talents and capabilities have been overshadowed by the strong passing attack from Nussmeier and the receivers. This guy can really run, and with a very talented offensive line that he gets to run through, his life becomes much easier on the field. That’s why I believe that, even at minus odds, taking him to score a touchdown should certainly earn a return. What stands out most about Durham is his blend of vision and burst, as he consistently identifies running lanes and accelerates through them in a way that puts constant pressure on opposing linebackers. While LSU has been praised for its aerial game, having someone like Durham forces defenses to stay honest, preventing them from dropping extra defenders into coverage to contain the passing game. In a game like this one, where both defenses will likely sell out to eliminate explosive plays, it’s often the dependable running back who makes the difference, converting third-and-shorts and keeping drives alive. Durham’s touches may not outnumber those of the receivers, but his efficiency and ability to find the end zone in critical moments should give LSU a reliable offensive balance. If Florida’s defensive front can’t contain him early, he could be the one who tips the momentum LSU’s way.

Prediction

LSU seemed like they were one of the favorites for the national title following a huge road win at Clemson, but after their letdown performance at home against Louisiana Tech and Clemson’s ugly win over Troy, last week arose questions for both teams as many are wondering if either were really that good in the first place. Florida, on the other hand, looked like a perfect candidate for a breakout season, but with an upset loss to USF and a much tougher schedule ahead, people are worried if Florida can even finish with a winning record in 2025. Both of these teams carry the burden of proving themselves after up-and-down starts, and the stakes could not be higher with the SEC race already taking shape. LSU’s defense has shown flashes of dominance but has yet to put together a complete four-quarter performance, while Florida’s offense has sputtered at key moments and failed to establish an identity. This matchup offers each program the chance to reassert itself as a contender, but it will require discipline, execution, and composure in a hostile environment. I’m expecting both offenses to be pretty slow again, and while I do believe Florida will keep it very close with LSU, Death Valley at night is just going to be too much for the Gators.

Final Score: #3 LSU 24, Florida 19

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#16 Texas A&M @ #8 Notre Dame (-6.5) (O/U: 50.5)

Notre Dame Stadium, South Bend, IN

7:30 pm, NBC/Peacock

After a bye week to regroup following their opening loss to Miami, Notre Dame finally gets their chance at a statement win in their first home game of the season, though Texas A&M is widely considered a team capable of competing with almost anyone in the SEC and beyond. The Irish know the stakes are high, especially since, as an independent, they don’t have the cushion of a conference title to strengthen their playoff résumé, making games like this critical. CJ Carr showed flashes of poise in the Miami game despite being pressured often, and with added preparation time, he’ll need to prove he can execute against an Aggie defense that has been inconsistent but still has the speed to disrupt. Notre Dame’s offense must establish balance, with Jeremiyah Love and Jadarian Price giving them a steady rushing attack that can wear down the Aggie front seven, while tight end Eli Raridon and receivers Jaden Greathouse and Malachi Fields work to create mismatches in the defensive backfield. Defensively, the Irish face the challenge of containing dual-threat quarterback Marcel Reed, who already has eight touchdown passes through two games and is dangerous when extending plays outside the pocket. Both teams are desperate for a signature win, and with energy high from kickoff, this game should hinge on discipline and execution in the biggest moments.

Best Bet: Notre Dame -6.5

Although Texas A&M is viewed by many as a dangerous upset pick and a team to monitor as the season progresses, I’m not fully sold on them yet. The Aggies have a history of struggling against elite defenses, and considering how much Marcus Freeman emphasizes discipline and physicality on that side of the ball, Notre Dame is well-positioned to make life difficult for their offense. Carr also showed flashes of poise against a strong Miami defense, and pairing him with the healthy dynamic duo of Love and Price in the backfield gives the Irish balance that A&M may struggle to contain. Where this matchup really leans Notre Dame’s way is in the trenches, with a defensive front capable of collapsing the pocket and forcing Reed into rushed throws against a disciplined secondary. On offense, the Irish ground game should steadily wear down an Aggie defensive line that has talent but lacks the depth to rotate effectively. Notre Dame’s ability to finish drives should also be noted, particularly with Love’s explosiveness complementing Price’s strength, giving Carr reliable outlets when the passing game stalls. Even with A&M showing improvement, the Irish’s combination of a maturing quarterback, proven running backs, and consistent defensive execution makes them the safer side to back, with composure in key red-zone situations likely to be the difference.

Prediction

This matchup has defensive battle written all over it, with the outcome hinging on which side can make a few more plays in the game’s most critical moments. Notre Dame’s recent big-game experience, including last season’s win over A&M in College Station, makes them the steadier and more trustworthy side. The Irish know how to handle the spotlight, and their disciplined defense paired with a balanced offense provides more reliable paths to victory than an Aggie team that remains talented but inconsistent under Mike Elko. Reed’s mobility and hot start to the season could create problems, but Notre Dame has the personnel to contain him and force A&M into third-and-long situations, where the Aggies have often struggled. On offense, the Irish may not light up the scoreboard, but a steady ground game combined with giving Carr the ability to pick his moments through the air should allow them to control tempo and limit mistakes. The atmosphere of South Bend in their first home game since last year’s College Football Playoff First Round game against Indiana, coupled with a roster already tested under postseason pressure, gives the Irish an additional edge. While this matchup may stay tight well into the second half, Notre Dame’s poise and execution in high-pressure moments should allow them to gradually pull away, closing the door on any Aggie comeback attempt and keeping their path back to the CFP alive.

Final Score: #8 Notre Dame 28, #16 Texas A&M 16

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Vanderbilt @ #11 South Carolina (-2.5) (O/U: 48.5)

Williams-Brice Stadium, Columbia, SC

7:45 pm, SEC Network

There’s been a good bit of talk about this specific game from Diego Pavia, and now that he and the Commodores are 2-0 off of a big blowout road win over Virginia Tech, it’s put up or shut up time against a South Carolina team that they struggled with last season in Nashville. Although this is a different look for the Gamecocks, they seem a little more balanced with a lot more promise, and now that they’re preparing for SEC play, they have a chance to tune things up before their schedule begins getting tough late. Vanderbilt enters this matchup riding the momentum of consecutive wins, with Pavia operating efficiently both through the air and on the ground, complemented by Sedrick Alexander’s explosive running. Meanwhile, South Carolina, under Shane Beamer, is still fine-tuning an offense led by LaNorris Sellers, whose dual-threat ability can create problems if the Gamecocks find early rhythm. Both teams will lean on their emerging offensive weapons while trying to limit mistakes, and the matchup promises to be close, with special teams, turnovers, and timely execution likely determining who can build an edge before heading into the heart of their respective schedules. The stakes are high for Vanderbilt, who are still seeking their first win in Columbia since 2008, and South Carolina will be eager to assert control early at home.

Best Bet: Eli Stowers o42.5 Receiving Yards

Pavia might be the face of this Vanderbilt team, but the real star is tight end Eli Stowers, who began this 2025 season as one of the nation’s best at the position and one of the favorites to win this year’s John Mackey Award. As long as this game stays competitive, many of the team’s play designs might favor him a pretty good deal, so in this spot, I believe he could earn himself a lot of targets, which could lead to plenty of yards considering how athletic of a tight end he is. Stowers has already shown he can stretch the field and create separation against slower defenders, and Vanderbilt’s coaching staff has consistently featured him in both passing and play-action concepts. While South Carolina’s defense has talent on the edge and in the secondary, they are still integrating new starters, which could leave openings in intermediate zones where Stowers thrives. Additionally, with Pavia’s precision and Alexander’s effectiveness in the ground game, defenses must account for multiple threats, giving Stowers more opportunities to find space and rack up yardage. Given the expected competitive pace and the Commodores’ reliance on balanced attack concepts, betting on Stowers to surpass receiving yardage projections presents a strong value in a matchup where his skills are likely to be showcased prominently.

Prediction

Vanderbilt is going to be just fine this year and should once again put themselves in contention for a second straight bowl appearance, which is no small feat for a program that struggled for so long to find consistency. Diego Pavia’s presence, along with a core of veteran playmakers, ensures that the Commodores will have chances to win some of the bigger games on their schedule. However, this matchup sets up as a difficult spot, especially with Pavia openly admitting that South Carolina is circled on their calendar for next weekend. That creates a real possibility of Vanderbilt getting caught looking ahead, and in an environment as hostile as Lane Stadium, any slight distraction can be costly. Virginia Tech doesn’t have the firepower to turn this into a shootout, but they don’t need to. The Hokies will rely on their running game, the steady growth of Kyron Drones, and a defensive front capable of creating constant pressure to wear down Vanderbilt’s offensive line. Expect a lower-scoring contest where possessions are at a premium, both sides leaning on their ground games and defenses to control the flow. In the end, the crowd should be the difference, as the Hokies take advantage of Vanderbilt’s mistakes and close out a much-needed win for their confidence just a few weeks before they begin conference play.

Final Score: #11 South Carolina 27, Vanderbilt 23

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Duke @ Tulane (-1.5) (O/U: 52.5)

Yulman Stadium, New Orleans, LA

8 pm, ESPN2

Tulane might be one of the Group of Five’s best and Duke might’ve gotten blown out, but Mensah had this game circled on his calendar a while ago and will make sure he’s ready to take down his former team. From a betting perspective, one of the best angles is quarterback-specific props, particularly Mensah’s passing yards total, which looks primed for the over given his volume so far this season. Through his first two games, he has already surpassed 700 yards through the air while completing over 70% of his throws, consistently connecting with Andrel Anthony and Que’Sean Brown on deep routes. Tulane’s defense, though strengthened by portal additions and disciplined at linebacker and safety, still shows vulnerability at corner, which opens chances for Duke’s receivers to create explosive plays. The Green Wave gave up more than 400 total yards to South Alabama despite winning that game, a sign that their defense can bend against dynamic offenses even if it doesn’t completely break. While Tulane will look to its front seven to apply pressure and limit Mensah’s time in the pocket, his familiarity with their defensive tendencies provides an extra edge. With Duke leaning on his arm to establish rhythm and sustain drives, a play on his passing over makes statistical sense and fits the narrative of a quarterback determined to prove himself against his old team.

Best Bet: Duke ML

Tulane might be one of the Group of Five’s best and Duke might’ve gotten blown out, but Mensah had this game circled on his calendar a while ago and will make sure he’s ready to take down his former team. From a betting perspective, one of the best angles is quarterback-specific props, particularly Mensah’s passing yards total, which looks primed for the over given his volume so far this season. Through his first two games, he has already surpassed 700 yards through the air while completing over 70 percent of his throws, consistently connecting with Andrel Anthony and Que’Sean Brown on deep routes. Tulane’s defense, though strengthened by portal additions and disciplined at linebacker and safety, still shows vulnerability at corner, which opens chances for Duke’s receivers to create explosive plays. The Green Wave gave up more than 400 total yards to South Alabama despite winning that game, a sign that their defense can bend against dynamic offenses even if it doesn’t completely break. While Tulane will look to its front seven to apply pressure and limit Mensah’s time in the pocket, his familiarity with their defensive tendencies provides an extra edge. With Duke leaning on his arm to establish rhythm and sustain drives, a play on his passing over makes statistical sense and fits the narrative of a quarterback determined to prove himself against his old team.

Prediction

Tulane has been one of the Group of Five’s top teams for the past four seasons now, and Jon Sumrall’s 2025 squad is more motivated than ever to take down their former starting quarterback for their second Power Four win this season. However, Mensah and Duke head coach Manny Diaz will give the Green Wave all they can handle for 60 minutes as they try to put last week’s embarrassment behind them. Tulane’s ability to control the line of scrimmage makes them dangerous, as their ground game can dictate tempo and keep defenses honest, but the lack of a consistent passing threat could limit them in a matchup where explosive plays may be required. Duke, by contrast, has the advantage of a quarterback who can stretch the field vertically while also leaning on a capable rushing tandem in Jaquez Moore and Peyton Jones, giving the Blue Devils balance that Tulane may struggle to match. Defensively, Duke must rebound after surrendering 45 points to Illinois, but with playmakers like All-ACC-caliber defenders Chandler Rivers and Vincent Anthony Jr., Diaz has the tools to dial up a stronger game plan against a run-heavy attack. This one should stay close, but Duke’s depth and ability to deliver in high-pressure moments tilt the outcome their way. While Tulane will fight for all four quarters, Duke is the better, more complete team, and Mensah will do whatever it takes to earn a win that will feel sweet for a while.

Final Score: Duke 31, Tulane 24

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Minnesota (-2.5) @ California (O/U: 40.5)

California Memorial Stadium, Berkeley, CA

10:30 pm, ESPN

One of the final games the Week 3 lineup is at one of the Atlantic Coast Conference’s Pacific coast venues, as California hosts Minnesota in a clash of two teams showcasing first-year starting quarterbacks at programs looking to break away from the middle of the pack towards the top half of their respective conferences. For the Golden Gophers, redshirt freshman Drake Lindsey has been steady in his first two outings, completing more than 60% of his passes while pushing the ball vertically to transfer receivers like Javon Tracy and Malachi Coleman. The Gophers’ passing game may still be developing, but Lindsey benefits from a proven rushing attack that has long been PJ Fleck’s identity, whether Darius Taylor is available or not. California, meanwhile, is leaning on five-star talent Jaron-Keawe Sagapolutele, who has shown composure against lighter competition but now faces his first true defensive challenge. His accuracy has been strong early, yet the Golden Bears’ offense is still trying to create rhythm with a largely rebuilt group of skill players. Both teams have shown flashes of balance on offense and resilience on defense, and with physical play expected in the trenches, the game could hinge on which young quarterback settles in first.

Best Bet: Jacob De Jesus o3.5 Receptions

I was initially planning to take Taylor’s rushing yards, but then I heard there was a chance that he wouldn’t play, so I went a different route with Cal wideout Jacob De Jesus and for him to catch at least four passes. Through two games, De Jesus has been one of Sagapolutele’s most reliable outlets, showing his quickness out of the slot and ability to turn short routes into chain-moving gains. His knack for creating separation in tight coverage has already made him the go-to target when the Bears need to keep drives alive, and his versatility allows the coaching staff to line him up in different spots to take advantage of defensive mismatches. Against a Minnesota secondary that lost a couple of key starters from last season, his shiftiness gives Cal a chance to exploit openings, particularly if the Gophers send heavy pressure at the line of scrimmage. The Bears have spread the ball around early in the season, but De Jesus has consistently drawn high-percentage looks, and his growing chemistry with Keawe-Sagapolutele should only strengthen in a matchup where he’ll likely serve as a safety blanket against Minnesota’s aggressive front. If Cal’s offense is going to find rhythm and consistency against one of the Big Ten’s stingier defenses, it starts with their most dependable receiver, and four or more catches feels like a strong possibility.

Prediction

The game is going to be pretty slow-paced, ultimately resulting in a defensive battle and not a whole lot of scoring. Cal’s offense has potential to be decent, but Minnesota’s defensive group is one of the better units in the B1G and will give Keawe-Sagapolutele plenty of trouble as he faces his first real test of a defense as a college quarterback. The Gophers’ defensive line has been dominant through two weeks, led by Anthony Smith off the edge and Deven Eastern plugging gaps inside, and their ability to collapse the pocket could disrupt California’s timing. On the back end, safety Koi Perich quickly emerged as a versatile playmaker last year and is more than capable of both erasing big plays and creating turnovers, something that could frustrate an inexperienced passer. For Cal, the defensive front will try to keep Minnesota’s rushing attack contained, but their secondary has been rebuilt almost entirely through the portal, and Minnesota has enough perimeter weapons to challenge them vertically. Both sides will look to lean on their ground games, but Minnesota’s experience in close contests and its proven defensive identity under Fleck provide a slight edge. Even without Taylor, AJ Turner is more than capable of churning out yards for this Golden Gopher ground attack, and he will be the difference maker as Minnesota gets a key road win in a tight slugfest.

Final Score: Minnesota 21, California 17

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Make sure to stay tuned this weekend as we learn about more of college football’s top teams and as we are now starting up conference play across the FBS!