The second week of the 2025 NFL season continues the league’s trend of loading drama early, with another slate packed full of storylines that extend beyond the standings. Divisional clashes will once again stir rivalries and test early-season poise, while several coaches and players find themselves squaring off against their former teams in emotional, high-stakes reunions. The week’s centerpiece, though, needs no extra buildup: a Super Bowl LIX rematch between the Eagles and Chiefs, with Jalen Hurts, Saquon Barkley, and the reigning champions traveling into Arrowhead to face Patrick Mahomes, Travis Kelce, and a Kansas City team determined to rewrite February’s heartbreak. From battles for bragging rights to familiar faces in unfamiliar uniforms and the league’s two heavyweights colliding under the prime-time spotlight, Week 2 offers no shortage of compelling angles. Once again, every matchup will not only provide insight into team identities but also shape the rhythm of an NFL season already brimming with tension and expectation. Let’s dive into the full slate with previews, favorite props, and final score predictions for another packed weekend of football:

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Thursday, September 11

Commanders @ Packers (-3.5) (O/U: 48.5)

Lambeau Field, Green Bay, WI

8:15 pm, Prime Video

After an opening weekend that lived up to its billing, we now get ready to begin Week 2 in Green Bay, what’s normally a frozen tundra for most of football season but will be a little warmer this time, in a matchup that has the Commanders traveling north to face the Packers. Washington is coming off a somewhat uneven showing against the Giants, where Jayden Daniels’ numbers looked solid but the offense as a whole never fully found its rhythm until late in the second half. That sort of inconsistency will not fly in Lambeau, especially against a Green Bay defense that looked fast, aggressive, and opportunistic in a statement win over Detroit. For Matt LaFleur’s group, Jordan Love picked up right where he left off last season, distributing the ball with efficiency while Josh Jacobs provided a steady foundation in the ground game. The Packers’ balance on both sides of the ball makes them look like early contenders in the NFC, but Washington’s depth and defensive toughness under Dan Quinn ensures this will not be a walkover. The game’s intrigue lies in whether Daniels can respond to the energy of Lambeau, extend drives with his legs, and generate enough big plays to keep pace with Love’s composure and the Packers’ polished execution.

Best Bet: Jayden Daniels o8.5 Rush Attempts

For the second Thursday night in a row, I am looking deep into someone’s rush attempts line, but instead of a running back, I’m going with a quarterback in Jayden Daniels to rack up at least nine carries. His dynamic mobility is already one of Washington’s most reliable weapons, and on a short week, expect Kliff Kingsbury to lean into that skill set as a way of keeping the Packers’ front seven honest. Daniels has shown an ability to escape collapsing pockets and turn broken plays into positive yardage, but against a Green Bay defense headlined by Micah Parsons and Rashan Gary, that improvisation may become more necessity than luxury. Even when Washington leans on Jacory Croskey-Merritt, Austin Ekeler, and even Deebo Samuel to contribute to a hefty, but effective ground game, Daniels’ rushing floor remains high because of designed quarterback runs and red-zone packages that put the ball in his hands. The Packers are disciplined in coverage, which could force Daniels to tuck and run more often than he prefers, especially on third down. With the Commanders’ offensive line still building chemistry and Lambeau’s crowd noise threatening to complicate protections, Daniels reaching nine carries feels less like a gamble and more like a strategic inevitability.

Prediction

What makes this matchup so fascinating is the contrast between Washington’s youth-driven explosiveness and Green Bay’s growing identity as a balanced, playoff-caliber roster. The Commanders will push the tempo and create some highlight moments with Daniels and Deebo Samuel working in space, but sustaining long drives in Lambeau requires precision that can be tough to summon on a short week. Love’s command of the Packers’ offense should allow Green Bay to control stretches of the game and put consistent pressure on Washington’s defense while they try and give Jacobs a rest following his significant workload just a few days ago against the Lions. Yet for all the Packers’ early-season promise, Daniels’ knack for making the kind of game-breaking plays that tilt momentum can’t be ignored, especially when combined with a defense that thrives on timely stops. In the end, Washington’s ability to squeeze a few more explosive moments out of its offensive engine should be enough to steal this one late, reminding the league that the Commanders are not just a one-year wonder but a team intent on belonging in the NFC’s upper tier. I’m expecting another lower-scoring game for both of these teams, who are playing on a short week without nearly as much preparation as usual, and while I think the Packers are built for lots of success at home in the long run this season, they’ll drop this one as the Commanders pull off the upset in Green Bay.

Final Score: Commanders 23, Packers 21

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Sunday, September 14

Browns @ Ravens (-11.5) (O/U: 44.5)

M&T Bank Stadium, Baltimore, MD

1 pm, CBS

This AFC North clash feels like two different stories colliding in Baltimore, even with both teams suffering heartbreaking one-point losses. Cleveland heads into Week 2 still haunted by what slipped away at home against Cincinnati, a defeat that highlighted the Browns’ persistent issues with finishing drives despite an inspired performance from veteran quarterback Joe Flacco. He spread the ball efficiently, piling up close to 300 passing yards while leaning heavily on rookies Dylan Sampson and Harold Fannin Jr., but the offense once again failed to find balance on the ground, leaving their defense to shoulder too much of the load. Now they walk into M&T Bank Stadium, where the Ravens arrive licking their wounds from a heartbreaking shootout loss in Buffalo, a game they controlled until Derrick Henry’s fumble flipped the script. For three quarters, Baltimore looked like the AFC’s most complete team, especially with Lamar Jackson carving up the defense through the air and on the move, Henry bulldozing his way past arm tackles, and Zay Flowers torching defenders in space, but a late collapse raised the question of whether this group can finally finish when it matters. Both teams are desperate to reset momentum, but the Ravens’ ceiling and firepower make this matchup feel like a measuring stick for Cleveland, one where a scrappy effort may not be enough against a roster built to chase the Lombardi Trophy.

Best Bet: Joe Flacco o241.5 Passing Yards

Flacco’s return to Baltimore adds a layer of nostalgia, but it also presents an intriguing betting angle. He may be 39, but last week showed he still has enough arm strength and decision-making to carry Cleveland’s offense, especially when the run game is nonexistent. Completing 31-of-45 passes for 290 yards against Cincinnati, Flacco leaned on quick-hitting throws to Jeudy, Sampson, and Fannin, keeping the offense afloat despite constant pressure. That volume isn’t going away, because the Browns are likely to play from behind again, and Kevin Stefanski will have little choice but to keep the ball in his quarterback’s hands. Baltimore’s secondary, on paper, is loaded with talented backs Jaire Alexander, Marlon Humphrey, Nate Wiggins, and Kyle Hamilton, but cohesion has not been its strong suit in recent years. Even last week, Josh Allen exploited breakdowns in coverage, stretching them vertically and forcing mismatches underneath. Flacco doesn’t need to hit home runs to clear this number; he simply needs time to continue finding his backs and tight ends in rhythm, racking up chunk plays across the middle of the field. Given Cleveland’s weak rushing attack and Baltimore’s aggressive pass rush, the Browns’ best path to survival is volume through the air, which sets up Flacco to eclipse 242 yards once again in what could become another long afternoon for his team.

Prediction

The Ravens are coming into their home opener with a sour taste from Buffalo, but their response feels inevitable, given the depth of talent across their roster and the urgency of bouncing back in front of a home crowd. Lamar Jackson remains the central problem for defenses, a quarterback who can dissect coverages with his arm before punishing defenders with backbreaking scrambles, and his connection with Flowers and Hopkins gives Baltimore more explosive options than in years past. Add in Henry’s bruising presence, and Cleveland’s defensive front, even with Garrett at the peak of his game, will be stretched thin trying to account for every threat. On the other side, Flacco will keep the Browns competitive for stretches, leaning on rhythm passing to chew up yardage and keep the chains moving, but asking him to outduel Jackson feels like asking too much. Baltimore’s defensive front is too deep, and its linebackers too disciplined, to let Cleveland’s offense dictate terms for long, which means at some point the mistakes that doomed the Browns in Week 1 will resurface. The Ravens, fueled by frustration and eager to prove that last week was a fluke, have the firepower and coaching to pull away decisively. This game won’t be close, and Baltimore will take care of business to set the tone for divisional play.

Final Score: Ravens 31, Browns 13

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Bills (-6.5) @ Jets (O/U: 46.5)

MetLife Stadium, East Rutherford, NJ

1 pm, CBS

Another AFC East clash sets the stage in East Rutherford, where the Bills arrive carrying the momentum of one of the most unforgettable opening-weekend wins in recent NFL memory, and the Jets return home still haunted by a gut-wrenching collapse against Pittsburgh. Buffalo’s win over Baltimore was the kind of performance that defines a season in September, as Josh Allen carried his team from the brink of disaster with poise and brilliance that reminded everyone why he’s the reigning MVP, yet the emotional toll of such a dramatic comeback raises questions about whether this week brings a hangover effect. On the other side, the Jets may be licking their wounds, but they showed real progress offensively under Aaron Glenn and Tanner Engstrand, with Justin Fields looking comfortable in a scheme tailored to his strengths and Breece Hall once again proving himself as one of the league’s most dynamic backs. The Jets defense, though flawed in the secondary, still flashes bite with Quinnen Williams anchoring the front, and the motivation of bouncing back at home in Glenn’s second game in charge can’t be overlooked. This isn’t just another early-season divisional meeting; it’s a test of resolve for Buffalo and a chance at redemption for a Jets team desperate to prove that Week 1’s heartbreak was more a growing pain than a warning sign.

Best Bet: Jets +6.5

The Bills are the superior roster, but this matchup feels tailor-made for a letdown spot, as Buffalo rides into MetLife Stadium following the adrenaline-soaked high of last week’s comeback thriller while the Jets stew in the sting of a game they felt was theirs until the final minute. Teams coming off emotional, high-profile wins often struggle to immediately replicate the same energy, and the Jets’ offensive growth in Week 1 suggests they have enough balance to keep this close throughout. Fields’ efficiency as a passer combined with his improvisational rushing ability forces defenses to stay honest, and pairing that with Breece Hall’s explosiveness creates problems for a Bills front seven that had difficulty handling Baltimore’s power run game before tightening up late. Garrett Wilson’s health remains the biggest variable, but even if he is limited, Engstrand’s system gives Fields multiple tight end and slot options to sustain drives. The Jets’ offensive line is far from airtight, yet their ability to move the pocket and use motion to manipulate Buffalo’s linebackers should open opportunities for chunk plays, particularly if Sauce Gardner and the secondary can slow Allen’s rhythm enough to keep the score within one possession. Betting on Buffalo to win makes sense, but trusting them to win comfortably in back-to-back emotional spots feels risky, especially against a hungry team playing its home opener with something to prove.

Prediction

The Bills are bringing with them the confidence of a team that just toppled Lamar Jackson in prime time, yet the NFL rarely allows for smooth sailing, and this divisional matchup presents its own challenges. Josh Allen will get his chances, because even with Sauce Gardner locking down one side of the field, Buffalo’s depth at receiver and Dalton Kincaid’s growing role as a mismatch weapon make sustaining drives likely, particularly if James Cook establishes rhythm on early downs. But New York’s defense is built to bend and frustrate, with Quinnen Williams crashing the pocket and the linebacker unit flying sideline to sideline, and if Fields takes care of the ball while Breece Hall controls tempo, the Jets can drag Buffalo into the kind of game where one turnover or special teams play decides it late. Allen’s knack for late-game heroics will once again play a big role here, and his ability to improvise outside of structure has bailed Buffalo out countless times before, yet the Jets’ energy in front of their home crowd ensures this won’t be an easy climb. Even though I believe the Jets will once again keep this game competitive, the Bills will find a way to survive with Josh Allen starring once again.

Final Score: Bills 27, Jets 24

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Jaguars @ Bengals (-3.5) (O/U: 48.5)

Paycor Stadium, Cincinnati, OH

1 pm, CBS

One of the most intriguing matchups this weekend unfolds in Cincinnati, where the Bengals host their home opener against a Jaguars squad trying to prove their Week 1 performance wasn’t just a byproduct of facing a rebuilding Panthers team. Jacksonville’s fresh start under Liam Coen has already given the offense a sharper rhythm, leaning on Trevor Lawrence’s poise and Travis Etienne Jr.’s explosiveness, but the trip to Ohio presents a very different kind of test. Cincinnati’s defense held up in Cleveland thanks to timely turnovers, but the real story is Joe Burrow and a passing attack that never got out of first gear, something that will need immediate correction against a Jacksonville secondary led by Tyson Campbell and rookie phenom Travis Hunter. The Bengals’ offensive line has been patched and retooled, but protection was shaky in spurts against the Browns, and now they face a Jaguars front with Josh Hines-Allen and Travon Walker looking to disrupt rhythm before Burrow can get Ja’Marr Chase and Tee Higgins going. For Jacksonville, the opportunity lies in controlling tempo and leaning on Etienne to force the Bengals’ linebackers into uncomfortable spots, while Cincinnati will be desperate to get back to the quick-hitting spread looks that made them one of the league’s most feared units last year.

Best Bet: Brian Thomas Jr. o73.5 Receiving Yards

If there’s one Jaguars player who looks built for this kind of spotlight, it’s Brian Thomas Jr., the breakout rookie from a year ago who wasted no time reminding everyone of his big-play ability. Jacksonville drafted him to stretch defenses vertically, something Trevor Lawrence has been missing for years, and his knack for attacking soft zones or beating single coverage makes him the kind of weapon who can tilt a game’s flow. Last season, Thomas finished near the top of the league in receiving yards as a rookie, and he enters this game with even more attention on him thanks to the arrival of Travis Hunter, whose presence often pulls coverage away. Against Cincinnati, the matchup looks especially favorable: Cam Taylor-Britt and DJ Turner are talented corners, but neither has the size-speed blend to consistently neutralize Thomas over four quarters. The Bengals’ defensive scheme under Al Golden emphasizes speed and gap discipline, but that aggressiveness can create one-on-one matchups downfield, and Lawrence has already shown more willingness to test them when Thomas is isolated. With Jacksonville likely playing from behind at some point in this one, expect plenty of targets in the second half, and given Thomas’ ability to flip the field with a single catch, topping 73.5 receiving yards feels like a strong play.

Prediction

The Bengals come into Sunday still searching for offensive rhythm, but the talent on that side of the ball is too overwhelming to stay bottled up for long, especially with Joe Burrow now facing a Jacksonville defense that remains talented but prone to lapses in coverage. The Jaguars showed encouraging balance in Week 1, yet the challenge of keeping pace with Burrow, Chase, and Higgins on the road is far steeper than managing Bryce Young and Carolina’s thin roster. Etienne can keep Jacksonville in it early with his burst and versatility, while Thomas provides the kind of downfield juice that could test Cincinnati’s secondary, but eventually the Bengals’ offensive line will stabilize, giving Burrow enough time to stretch the field and punish single coverage. On the other side, the Jaguars’ defense may generate some pressure, but without consistent stops on third down, their energy risks being sapped by Burrow’s ability to extend plays. This is the type of game where Cincinnati’s offensive depth finally reemerges, with Burrow rediscovering his chemistry with Chase after a muted opener, and the Bengals lean on their stars to finish strong at home.

Final Score: Bengals 31, Jaguars 27

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Rams (-5.5) @ Titans (O/U: 41.5)

Nissan Stadium, Nashville, TN

1 pm, CBS

The Rams travel across the country to Nashville for their first road matchup of the season against the Titans, and with an offense that offers clear upside, a young defense growing into one of the league’s stingiest units, and a coach who has proven how to scheme his way out of tough spots, Los Angeles projects as a dangerous road opponent. Matthew Stafford, still precise in timing and decisions when protected, pairs with Puka Nacua and Davante Adams to create a receiving hierarchy that can flex between short-area rhythm and explosive downfield shots, while Kyren Williams supplies a workmanlike rushing identity that keeps opponents honest and sustains drives. On the other side, Tennessee is very much in a foundational year under Brian Callahan, and last week’s trip to Denver exposed growing pains in pass protection and receiver continuity as rookie Cam Ward absorbed a heavy workload, though the Titans do boast playmakers such as Jeffery Simmons up front and L’Jarius Sneed in the secondary. This clash feels like the sort of early-season measuring stick that separates teams with clear playoff blueprints from those still building one, and the contrast between a Rams roster trending upward and a Titans unit searching for identity should make for a fascinating, if uneven, afternoon in Nashville.

Best Bet: Kyren Williams o75.5 Rushing Yards

I picked Kyren last week to score a touchdown against Houston, which he delivered, and as the most consistent offensive performer in Sean McVay’s scheme, I’m back on him to eclipse 75.5 rushing yards here, especially given how the Rams are likely to manage the clock and lean on a ground approach when they take a lead. Williams combines the vision and sudden burst needed to exploit interior seams, while Los Angeles’ offensive line has shown the capacity to open up those lanes even against front sevens with athletic linebackers, and that physicality should be magnified in a matchup where Tennessee will try to answer in kind. Tennessee’s defensive rotation features talent, but it remains young and occasionally undisciplined in gap responsibilities, which plays directly into Williams’ strengths on inside zone reads and timely cutback lanes. Moreover, the game script projects the Rams to control possession for extended stretches, giving Williams the volume he needs to reach this mark, and McVay’s history of relying on trusted backs in short-yardage and red-zone situations increases the likelihood of early touchdowns and consistent carries. With his reliability to break out for big runs, along with the fact that they likely won’t find themselves trailing for at least the majority of this game, I would be surprised if Williams doesn’t reach at least 80 on the ground.

Prediction

Expect the Rams to prioritize ball control and situational football, using their ground game and timely play-action to keep Tennessee off balance while Matthew Stafford dials up high-percentage throws that sustain long, clock-consuming drives. As the contest progresses, Los Angeles’ offensive line should increasingly dominate interior matchups, enabling both a steady rushing cadence and the occasional vertical shot to Nacua or Adams that forces the Titans to respect the entire field, which in turn opens creases for designed runs and misdirection runs near the goal line. Tennessee will not be without answers, as Ward’s mobility and the Titans’ playmakers can manufacture sudden momentum swings, yet sustaining that success will require consistent pass protection and cleaner execution in the intermediate passing game than was evident last week. Defensively, the Rams have the scheme versatility to disguise pressures and rotate personnel in ways that create confusion pre-snap, and those tactics should translate into a few third-down stops that tilt field position. Clock management and possibly special teams won’t matter a ton until late, and with Los Angeles better equipped to avoid self-inflicted mistakes, the visitors should be able to maintain a lead through the fourth quarter and secure a road win. Cam Ward will eventually figure things out, but it won’t be this week as the Rams spoil his home debut with the Titans.

Final Score: Rams 21, Titans 10

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Patriots @ Dolphins (-1.5) (O/U: 42.5)

Hard Rock Stadium, Miami Gardens, FL

1 pm, CBS

After a sobering Week 1, the New England Patriots arrive in Miami seeking redemption, facing a Dolphins team that likewise struggled to find its rhythm in a lopsided opener, and both squads enter this divisional clash eager to prove their mettle early in the season. New head coach Mike Vrabel, who has brought a fresh energy and steady leadership to the Patriots’ sideline, now relies on second-year quarterback Drake Maye to demonstrate growth and command a retooled offense that features the explosive addition of Stefon Diggs alongside emerging talents like Kayshon Boutte and DeMario Douglas, all of whom will be expected to create separation in a secondary anchored by Carlton Davis III with Christian Gonzalez likely to miss his second straight game. On the ground, Rhamondre Stevenson and rookie TreVeyon Henderson are poised to carry a balanced rushing attack behind an offensive line blending youth and experience, while the Patriots’ defensive front led by Harold Landry III and Milton Williams will be tested by the speed and creativity of Miami’s motion-heavy schemes and athletic backfield. Both coaches know that divisional supremacy is often determined in these early matchups, and the ebb and flow of momentum, turnovers, and red-zone efficiency could be decisive in a contest that promises to combine strategy, physicality, and the inevitable emotional swings of a tightly contested AFC East duel.

Best Bet: De’Von Achane Anytime TD

Miami’s offense struggled to find consistent rhythm last Sunday, and it seems highly likely that head coach Mike McDaniel will lean more heavily on his explosive backfield weapon, De’Von Achane, to ignite the Dolphins’ attack and sustain offensive drives. Achane’s dual-threat ability makes him a constant scoring threat, particularly in short-yardage and red-zone situations, and he has the speed and agility to exploit seams both inside the tackles and on perimeter sweeps, which could be critical if Miami falls behind early. McDaniel’s offense, known for its timing-based motion and creative backfield schemes, often uses the run to manipulate defensive fronts and open passing lanes, meaning Achane’s opportunities could be amplified as defenders are forced to respect multiple threats. On the other side, New England’s defensive front, anchored by Harold Landry III and Christian Barmore, will need to maintain discipline, balancing aggressive pass-rush duties against coverage responsibilities, which may create openings for Achane to turn modest gains into explosive plays. Additionally, sustained drives and third-down conversions could funnel even more touches to Miami’s versatile backfield, keeping the Patriots’ defense on its heels while allowing Achane to dictate tempo and control momentum. Given his proven explosiveness and the Dolphins’ reliance on his playmaking, there is a strong case for Achane reaching the end zone at least once, making him a compelling prop to monitor while the Dolphins adjust and New England tries to respond under Vrabel’s first-year system.

Prediction

The Patriots enter Miami looking to rebound from a narrow Week 1 defeat, but the Dolphins’ mix of speed, scheme creativity, and opportunistic playmakers creates a formidable challenge for a team still ironing out timing and cohesion under a second-year quarterback, while the Patriots’ defense, anchored by Landry, Barmore, and Williams, must balance aggression with discipline to avoid being exploited by quick passes and misdirection, and even with promising contributions from Diggs and Henderson, sustaining drives against a Dolphins unit that thrives on turnovers and explosive plays may prove difficult. Miami’s front seven, featuring Bradley Chubb and rookie Kenneth Grant, could dictate the tempo by generating pressure and forcing early reads, and Tua Tagovailoa’s ability to connect with Achane in space may further tilt the balance in the Dolphins’ favor, while the Patriots’ offensive line will need to protect Maye and create lanes for the rushing attack to keep pace. Both teams have the talent and coaching to compete, but the combination of Miami’s familiarity with home conditions, desire to rebound after a disappointing opener, and divisional intensity gives them a slight edge. Fans should expect a competitive, hard-fought matchup where mistakes are magnified, but ultimately, the Dolphins’ balance and explosiveness make them just enough of a step ahead to secure the victory, even if New England fights tooth and nail throughout the afternoon.

Final Score: Dolphins 23, Patriots 20

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Bears @ Lions (-6.5) (O/U: 46.5)

Ford Field, Detroit, MI

1 pm, FOX

For the second straight week, both Chicago and Detroit find themselves in a compelling NFC North clash, but this time, it’s against each other as the Bears travel to Ford Field to take on the Lions, with a storyline that’s as much about familiarity as it is about competition. Ben Johnson’s first season at the helm in Chicago immediately intersects with the franchise he helped orchestrate in Detroit, giving him both inside knowledge and a personal stake in the outcome, while the Bears’ young quarterback Caleb Williams and his supporting cast seek to find rhythm against a defense that has grown in continuity and talent under Kevin Sheppard. Chicago’s offense, blending timing routes, spacing, and a versatile back in D’Andre Swift, will face a Detroit front anchored by a healthy Aidan Hutchinson and Marcus Davenport, both expected to bring sustained pressure and edge disruption throughout the contest. Meanwhile, Detroit’s ground game, led by Jahmyr Gibbs and David Montgomery, will test a Bears defense still acclimating to Dennis Allen’s system and emphasizing simplified reads and opportunistic aggression. The matchup also pits wide pass-catching duos against each other, DJ Moore, Rome Odunze, and Cole Kmet versus Amon-Ra St. Brown, Jameson Williams, and Sam LaPorta, with both offenses eager to establish early flow in a game that has implications for early-season divisional positioning, morale, and momentum in arguably the most tightly contested division in the league.

Best Bet: Jahmyr Gibbs o68.5 Rushing Yards

Gibbs didn’t do hardly anything on the ground last week, particularly due to the fact that his team never had a lead, and most of his production came as a receiver with the most receptions on the team. Now, he gets an opportunity to make up what he missed out on last week, as he gets a home matchup against a Bears team that will probably find themselves trailing to Detroit for most of the four quarters, which is why I believe he will get lots of rushing yards with an increased workload ahead of David Montgomery. Gibbs’ dual-threat capability will be front and center, as the Lions are likely to find themselves leading early and allowing the running game to chew up the clock while protecting Jared Goff from unnecessary risk, creating ample opportunity for Gibbs to carry a significant load between the tackles. The Bears, despite flashes of disruption against the Vikings, struggled to contain inside runs and will face a back with the speed, vision, and burst to exploit both interior gaps and occasional perimeter looks. Detroit’s offensive line offers stable run blocking, while Montgomery can serve as a complementary piece that keeps defenses honest. Historically, when the Lions take control, sustained drives funnel through their lead backs, and Gibbs’ prior volume and explosiveness suggest he can eclipse the set threshold if Detroit executes a balanced, clock-managing approach. Considering the way the Bears’ front seven is still settling into a new coaching scheme and adjusting to rotational personnel, expect Gibbs to see plenty of touches, convert critical third downs, and push for possibly a triple-digit number in the yard column.

Prediction

The Lions bolster plenty of continuity on a roster built for both balance and toughness, which positions them to assert themselves over a Bears team still acclimating to Johnson’s vision and Williams’ growing command of the offense. Chicago showed flashes of creativity and pace in Week 1, particularly in their early drives and connection between Williams and his receivers, but seeing their fourth quarter collapse makes it noticeable that Detroit’s is much more disciplined and has a physical style and edge pressure that could force repeated difficult reads while keeping Williams from establishing comfort in the pocket. The Lions’ secondary should limit explosive plays and make the Bears earn every yard, while their offensive line and balanced backfield give Goff the tools to sustain drives and maintain possession. While Chicago’s rookie and second-year contributors offer tantalizing upside and Johnson will have personal motivation to push his team hard against his former franchise, the Lions’ blend of experience, cohesion, and adaptable schemes make them the more likely victor. The Bears will compete, show flashes of brilliance in spurts, and provide moments that excite fans, but Detroit’s versatility and explosiveness across all three phases should ultimately carry the day, leaving Chicago to regroup and continue building under a first-year regime.

Final Score: Lions 30, Bears 24

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Seahawks @ Steelers (-3.5) (O/U: 39.5)

Acrisure Stadium, Pittsburgh, PA

1 pm, FOX

For the second week in a row, one of the Steelers’ offseason marquee additions will have a chance to make a statement against his former squad, as DK Metcalf returns to face the Seahawks in a matchup charged with both personal motivation and divisional pride. The Seahawks head into Pittsburgh under second-year head coach Mike Macdonald still trying to establish a new identity after overhauling their roster, as a blend of veterans and young talent takes the field with the goal of improving on last year’s foundations. Sam Darnold remains the starting quarterback in Klint Kubiak’s modernized offense that he brings over from Houston, but the unit is still seeking cohesion, particularly after the departures of Tyler Lockett and Metcalf left significant voids in the passing game. Kenneth Walker III and Zach Charbonnet will share the backfield, offering a mix of explosive plays and consistent early-down work, while Cooper Kupp and Jaxon Smith-Njigba anchor a receiving corps that blends experience with rising talent. Defensively, Seattle relies on a revamped front seven and a secondary to mask depth issues, though consistency remains a concern. In Pittsburgh, Aaron Rodgers and a newly configured offense led by Arthur Smith aim to capitalize on mismatches and establish early momentum, with Metcalf poised to be the focal point. The combination of revenge narratives, divisional significance, and emerging talent creates a compelling backdrop for a high-stakes matchup that could set the tone for both teams’ early campaigns.

Best Bet: Under 39.5

While the Steelers opened the season with a surprisingly high-scoring win against the Jets, this clash projects to be far more methodical, as Pittsburgh’s offense is likely to control tempo against a Seahawks team that prides itself on disciplined, situational defense. Aaron Rodgers will command the huddle and spread the field efficiently, but the expectation is that his veteran-led attack will lean heavily on ball control and calculated play-action rather than quick, explosive shots downfield. Meanwhile, Seattle’s defense, still searching for consistent performance from its young linebackers and secondary, is likely to bend rather than break, funneling plays into Walker and Charbonnet to manage the clock and sustain drives. The running game figures to be a focal point on both sides, but particularly for the Steelers, where Jaylen Warren’s early-down work and plenty of depth behind him provide balance behind an athletic offensive line. Given the emphasis on extended drives, clock management, and the disciplined approach each defense is expected to bring, the scoring pace should remain measured, making the under a logical target. Both offenses still have plenty of promise, but the overarching principle remains for both coaching staffs that possessions will matter, resulting in the most effective teams being those that control the line of scrimmage and limit turnovers.

Prediction

The Steelers are still riding the confidence of a hard-fought road victory and armed with an offense led by a former MVP quarterback who has long thrived under pressure, particularly in scenarios that carry personal stakes or revenge narratives. DK’s return to face his former team only adds to the motivation for Pittsburgh, as the veteran wideout looks to make a statement in front of familiar fans while Rodgers leverages his experience to exploit matchups and maintain offensive efficiency. Meanwhile, Seattle is still attempting to blend its reworked offensive weapons into a cohesive, rhythm-driven scheme capable of withstanding the challenges posed by a disciplined, veteran-heavy Steelers defense. The Seahawks will flash potential through Darnold’s connection with his two talented weapons at wide receiver as well as Walker’s capability of breaking through when needed, but Pittsburgh’s combination of poise, depth at tight end, and a defensive front designed to confuse and pressure quarterbacks will make sustained Seattle drives extremely difficult to execute. Rodgers and Metcalf are both likely to produce critical plays in pivotal moments, yet the Steelers’ ability to dominate third-down situations, force timely mistakes, and control tempo through the calculated use of the run game provides them a measurable edge. Both defenses are capable of bending without breaking, but Pittsburgh’s balance of experienced leadership and emerging talent should allow them to dictate the pace, manage key possessions, and ultimately carry the home team to victory in a tense, hard-fought divisional battle.

Final Score: Steelers 20, Seahawks 17

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Giants @ Cowboys (-5.5) (O/U: 44.5)

AT&T Stadium, Arlington, TX

1 pm, FOX

After both being taken down by fellow NFC East rivals during Opening Weekend, the Giants and Cowboys will meet each other once again in Dallas, and with both teams navigating different transitional paths, this matchup carries far more intrigue than the lines suggest. The Giants enter with a retooled quarterback room led by Russell Wilson, whose veteran presence contrasts sharply with the young, dynamic offensive pieces around him, while second-year back Tyrone Tracy Jr. offers flashes of explosiveness despite a limited supporting cast. New York’s defense remains anchored by Dexter Lawrence II and Kayvon Thibodeaux, though consistency is a lingering concern for Shane Bowen’s unit. Dallas, meanwhile, is still finding its rhythm under first-year head coach Brian Schottenheimer and offensive coordinator Klayton Adams, who are blending a new-look backfield featuring Javonte Williams and Miles Sanders with a receiving corps led by CeeDee Lamb. The absence of Micah Parsons looms over the Cowboys’ defensive front, but the secondary, led by Trevon Diggs and DaRon Bland, showed promise last week in containing Jalen Hurts and company. The combination of divisional bragging rights, early-season momentum, and personnel storylines creates a game where every drive feels pivotal, and each team has reason to believe it can seize control while searching for identity in a league still finding its early-season rhythm.

Best Bet: Cowboys -5.5

The young talent on the Giants roster is promising, but Dallas’ familiarity with its own systems and the comfort of a home setting gives them a distinct edge. Last week’s narrow loss to the reigning Super Bowl champions in Philadelphia revealed both the Cowboys’ resilience and their ability to balance the run and pass effectively, particularly when Dak Prescott connects with CeeDee Lamb in rhythm. Javonte Williams and Miles Sanders give the offense versatility in both ground-and-pound and explosive-play scenarios, which could wear down a Giants front still adjusting to Wilson’s mobility and offensive timing. Meanwhile, New York’s defense is capable of flashes, but without consistent pressure or depth at key spots, slowing Dallas’ tempo will be a challenge. The focus here will likely be on controlling possession and sustaining drives, with the Cowboys’ offensive line expected to carve lanes for Williams and Sanders while allowing Prescott enough time to find Lamb and George Pickens on intermediate routes. Barkley-like opportunities won’t be there for New York, making Dallas’ early control and ability to win the trenches the driving factor behind this selection. The combination of home-field advantage, roster balance, and Dallas’ execution makes taking the Cowboys at -5.5 is the logical way to go.

Prediction

The Giants enter the second week with a glaring need to rebound after a disappointing opener, while the Cowboys are hoping to refine their identity and capitalize on near-misses from their first contest, which should make for a contest dominated by execution and mistakes. Dallas will likely ride the efficiency of Prescott and key playmakers to methodically move the ball, leaning on balanced rushing attempts to control the clock and force the Giants to play catch-up in both tempo and strategy. New York’s offensive line must hold up to give Wilson the necessary time to make reads and allow the backfield rotation to find traction, but lapses could quickly swing momentum toward the home team. Defensively, Dallas has the tools to generate pressure at critical moments and contain explosive plays, while the Giants will struggle to consistently create turnovers or sustain drives against a disciplined scheme still reeling from early adjustments. Russ will look a little bit better in his second start as a Giant, but he’ll throw a couple of picks to a stingy Cowboys secondary, which will be the difference here. Their home-field edge and ability to convert crucial situations should ultimately give them the victory as the drama in the NFC East continues to unfold early.

Final Score: Cowboys 27, Giants 16

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49ers (-3.5) @ Saints (O/U: 40.5)

Caesars Superdome, New Orleans, LA

1 pm, FOX

The 49ers earned themselves a massive win last weekend in Seattle over the Seahawks, but it came with a price as they’ll now be missing Brock Purdy and George Kittle for at least the next few weeks. San Francisco’s offense, already relying heavily on the dual-threat of Christian McCaffrey and the emerging Ricky Pearsall, will need to lean on its depth to maintain rhythm and efficiency against a Saints team eager to prove that last week’s close home defeat to Arizona was a fluke rather than a blueprint for the season. Klay Kubiak’s new offensive system will be tested early, as the Niners must adjust without their top receiving target and dynamic tight end, forcing more creative looks and pre-snap motion to keep New Orleans’ young secondary honest. Defensively, Nick Bosa and Fred Warner will again shoulder the load, aiming to disrupt the Saints’ developing quarterback situation while neutralizing Alvin Kamara’s running contributions and the deep threat of Chris Olave. On paper, New Orleans has talent, but the combination of inexperience at quarterback and a retooled offensive line could make sustaining long drives difficult, especially against a Niners front seven capable of generating pressure from multiple angles. The game is a litmus test for how well San Francisco can navigate adversity early in the season while keeping pace in a division that normally isn’t forgiving.

Best Bet: Under 40.5

With how much the 49ers are missing out of their passing attack and how inconsistent the Saints’ passing game has been under a newly installed system, this contest shapes up as a low-scoring affair in which defenses are poised to dominate the narrative from the opening snap, forcing both offenses to earn every yard through discipline and execution rather than relying on big plays to shift momentum. McCaffrey is expected to remain the centerpiece for San Francisco, grinding out tough yards between the tackles while compelling New Orleans’ linebackers to maintain gap discipline and avoid overcommitting, which could open lanes for the second-level running game and occasional play-action opportunities. Meanwhile, the Saints are likely to struggle to string together extended drives behind Spencer Rattler, particularly if the Niners’ pass rush consistently forces hurried throws or coverage breakdowns occur sporadically, as they did in Week 1, leaving the offense vulnerable to mistakes. New Orleans’ best hope lies in explosive plays from Olave or Kamara, but even those may be limited given the sustained pressure and disciplined tackling from a San Francisco front seven anchored by Bosa and rookie Mykel Williams. Both teams are expected to rely on methodical drives and clock management, a scenario that naturally keeps the score under the projected game total while allowing key playmakers to shine in critical moments without the game devolving into a shootout, ensuring that every possession carries outsized weight.

Prediction

Shorthanded and navigating key injuries, the 49ers will look to impose their balanced offense and disruptive defense on a Saints roster still searching for identity under a first-year coaching regime, a task that is certainly achievable but will require precision and discipline even against a team as overhauled as New Orleans. With both Purdy and Kittle sidelined, the burden of generating explosive plays and sustaining drives falls more heavily on McCaffrey and the remaining skill players, who must find ways to create momentum while the defensive unit works to contain Kamara and force the Saints’ young quarterback into uncomfortable situations, exploiting any lapses in protection or decision-making. Meanwhile, New Orleans is attempting to establish cohesion under head coach Kellen Moore, seeking to take advantage of a versatile backfield and a wide receiving corps that could spark occasional success, yet the team’s lack of experience and significant roster turnover make consistency a persistent concern and leave them vulnerable to mistakes in critical moments. Because turnovers, blown assignments, and short fields are likely to dictate the flow more than individual heroics, the game will hinge on preparation, depth, and health, with every possession carrying outsized importance as both teams work to define their early-season identity. Even without Purdy and Kittle, the 49ers’ combination of talent, resilience, and Shanahan’s winning mindset should be enough to secure a hard-fought road victory over the Saints.

Final Score: 49ers 16, Saints 13

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Broncos (-1.5) @ Colts (O/U: 43.5)

Lucas Oil Stadium, Indianapolis, IN

4:05 pm, CBS

The Broncos remain one of the NFL’s most well-coached teams and one of the best young foundations in football, but their performance last week left plenty to be desired, and Sean Payton knows that his group will need to raise its level quickly with a difficult road trip into Indianapolis. Bo Nix showed flashes of why Denver invested in him, but his rookie mistakes were just as evident, and against a Colts team that is playing with visible purpose, the margin for error shrinks considerably. The Colts are coming off a statement opener, where Daniel Jones, now quickly developing a strong reputation inside the organization and among the fanbase, lit up Miami in what doubled as an emotional tribute to Jim Irsay. Jones looked calm, confident, and in control, orchestrating an aerial attack that leaned on Michael Pittman Jr. and rookie tight end Tyler Warren while balancing tempo along with Jonathan Taylor’s bruising ground presence. Lou Anarumo’s defense suffocated the Dolphins and reminded everyone that Indianapolis can dominate in the trenches when firing on all cylinders. What makes this matchup compelling is the stylistic contrast is that Denver’s elite coverage unit trying to disrupt a suddenly efficient Colts passing game that now carries confidence. The real question is whether Nix and Payton’s offense can match the punch of an Indianapolis team that appears intent on proving Week 1 was no fluke.

Best Bet: Over 43.5

At first glance, the total feels almost like a trap, especially given Denver’s reputation for smothering passing attacks with a secondary that many consider to be one of the league’s best, if not the best. Most weeks, that combination erases windows and dictates tempo, but Daniel Jones represents a different kind of challenge than the Broncos faced in Cam Ward. He has shown a willingness to attack the middle of the field, extend plays with his legs, and spread the ball around to multiple outlets, and against quarterbacks who bring that dual-threat flavor, even elite defenses eventually bend enough to concede points. At the same time, Denver knows last week’s offensive performance cannot repeat itself, and they are fortunate that Indianapolis, while solid, doesn’t boast the same kind of dominant defensive front that Tennessee used to expose some of the Broncos’ flaws. Expect JK Dobbins and RJ Harvey to set an early tempo on the ground while Nix leans on quick throws to Courtland Sutton and Evan Engram in order to settle into a rhythm. The Colts will counter with Taylor’s physicality, but it is Jones’ improvisation inside the red zone that could tilt momentum toward fireworks. With both teams capable of sustaining drives while still striking suddenly, the over emerges as not just the logical play, but also the most entertaining bet for a game with real back-and-forth potential.

Prediction

This matchup has the feel of a tightrope game, one where every possession carries weight and neither team is willing to concede ground easily. For Indianapolis, this is not just another home opener, but a chance to prove that last week’s outburst was the start of something real, a validation that Daniel Jones was not held back in New York but is instead capable of guiding a franchise toward contention. With Taylor as a workhorse against Denver’s front and Pittman Jr. serving as the steady outlet, the Colts’ plan will be to wear down the defense while letting Jones improvise when the structure breaks. Denver, however, is chasing its own validation. After a shaky offensive debut, the Broncos must show they can complement what might be the AFC’s most dominant defensive unit, and Payton’s carefully scripted plan for Nix will be tested against a Colts defense that thrives on collapsing the pocket and forcing mistakes. Both sides will trade momentum, and both defenses will have stretches of control, but it is composure in the final minutes that will ultimately separate them. While the Colts’ energy and belief are undeniable, Denver’s defense has a way of tilting the field in critical moments. In the end, the Broncos get the late stop they need, escape with a narrow road victory, and carry their unbeaten start into a high-profile trip to Los Angeles next week.

Final Score: Broncos 26, Colts 24

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Panthers @ Cardinals (-6.5) (O/U: 43.5)

State Farm Stadium, Glendale, AZ

4:05 pm, CBS

For a team that many thought could quietly emerge as a fringe postseason contender by year’s end, the Panthers hardly resembled that vision in Week 1, looking flat and overwhelmed in a lopsided loss to a Jacksonville squad adjusting to its own new coaching staff. That performance not only exposed familiar weaknesses but also raised immediate questions about whether Carolina’s offseason moves were enough to spark genuine progress. Now, the challenge becomes even greater, as they head west to face a Cardinals team that is not only better coached and more balanced than Jacksonville but also carries the added boost of a home opener and a fan base energized by last week’s narrow road victory. Arizona has momentum, and they know it. With Kyler Murray settling back into rhythm, Marvin Harrison Jr. flashing his elite potential, and Trey McBride already proving himself as one of the more reliable tight ends in football, the Cardinals are brimming with confidence on offense. Meanwhile, their defensive front looks poised to exploit Carolina’s shaky protection, while the secondary has the talent to bait Bryce Young into mistakes if he continues to hesitate in his reads. For the Panthers, the formula is straightforward but daunting: they must protect Young, find offensive rhythm early, and somehow prevent Arizona from dictating the game’s pace. Anything short of that, and head coach Dave Canales could find his tenure facing uncomfortable questions sooner than expected.

Best Bet: Trey McBride o60.5 Receiving Yards

I seriously considered leaning toward James Conner’s rushing line for this matchup, especially given how porous Carolina’s run defense looked in Week 1, but the more I thought about it, the more I realized Drew Petzing’s offense is at its most dangerous when Murray is working off play action and manipulating defenders with his eyes. That style of play doesn’t just create opportunities for the run game; it opens passing lanes for Murray’s most trusted targets, and while Harrison will always command defensive attention, it may be McBride who quietly benefits the most if coverage consistently shifts toward the rookie star. McBride has already established himself as Murray’s security blanket, a tight end whose combination of size, sharp route-running, and yards-after-catch ability makes him a mismatch for almost any linebacker or safety tasked with covering him. Just last week, he saw nine targets and turned them into six catches for 61 yards despite the Cardinals’ offense stalling at times, and that kind of volume speaks volumes about the trust Murray has in him. Against Carolina, the matchup looks even more favorable, as the Panthers’ linebackers were consistently exposed in coverage against Jacksonville’s tight ends and backs. If Arizona’s offensive line struggles to keep Murray clean, expect him to lean on McBride even more with quick throws and intermediate routes, giving the tight end every chance to stack receptions and eclipse the 60-yard mark for his fourth game in a row, dating back to last December.

Prediction

I want to believe the Panthers will come into this matchup with enough urgency to put up a fight, but at the moment they look like a team still trying to figure out who they are, and unfortunately, that starts with Young. The second-year quarterback continues to play as if caught between instinct and hesitation, and while Carolina added pieces around him to help, the passing game still lacks rhythm and consistency. That uncertainty presents a perfect opening for an Arizona defense that may not be loaded with household names but is already showing discipline and cohesion under Jonathan Gannon. Rookie Will Johnson has flashed the ability to stick with receivers in man coverage, while veterans such as Budda Baker remain reliable leaders on the back end, creating a blend of youth and experience that feeds into their opportunistic style against a solid young receiving corps from Carolina. On offense, Murray doesn’t need to be spectacular for the Cardinals to tilt the field in their favor. Carolina may find a spark here and there, perhaps through a deep ball to rookie Tetairoa McMillan or a big run from Chuba Hubbard, but over four quarters, Arizona’s balance, confidence, and efficiency should be enough to secure control and deliver another statement win.

Final Score: Cardinals 27, Panthers 13

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Eagles (-1.5) @ Chiefs (O/U: 46.5)

GEHA Field at Arrowhead Stadium, Kansas City, MO

4:25 pm, FOX

The NFL couldn’t have scripted a more captivating Week 2 headline than a rematch of last February’s Super Bowl, only this time it unfolds under the bright lights of Arrowhead. Philadelphia rolls in as the defending champions, confident after grinding out a rivalry win against Dallas in Week 1, while Kansas City is still stinging from its São Paulo stumble to the Chargers. Nick Sirianni’s Eagles appear every bit as sharp as the squad that steamrolled its way to a Lombardi Trophy, blending Jalen Hurts’ dual-threat brilliance with a reloaded offense featuring Saquon Barkley’s thunderous running style and a deep, versatile receiving corps. Defensively, Vic Fangio’s young, fast unit showed it could clamp down in big moments against Dak Prescott last week, proving that even amid chaos, like Jalen Carter’s pregame ejection, the group is battle-tested and resilient. On the other side, Andy Reid and Patrick Mahomes have built a dynasty on creativity and consistency, but their Week 1 loss revealed cracks in timing and chemistry, particularly after rookie Xavier Worthy left early with injury. Still, the Chiefs’ offensive firepower, anchored by Mahomes, Hollywood Brown, and Travis Kelce, will always give them a chance, especially at home in a building that has become football’s loudest fortress. The atmosphere alone makes this matchup feel like a chance to prove staying power for Philadelphia and redemption for Kansas City.

Best Bet: Eagles -1.5

Choosing to side opposite Mahomes in Kansas City is never comfortable, yet the matchup dynamics lean toward Philadelphia. The Chiefs are still searching for rhythm, with an offensive line that looked shaky in Week 1 and a defense adjusting without several veteran anchors, while the Eagles already appear steady and physical, especially in games where they seize control in the trenches. The difference-makers here, however, could very well be Barkley and AJ Brown. Barkley proved against Dallas that he doesn’t need gaudy numbers to tilt a game’s balance, as his 18 carries, chain-moving consistency, and red-zone presence set up Jalen Hurts’ play-action attack. Brown, meanwhile, had an unusually quiet opener, not recording a catch until late, but that feels unlikely to repeat against a Chiefs secondary that struggled to contain Justin Herbert just a week ago. If Barkley forces Kansas City to stack the box, Brown will have opportunities to punish them vertically and in intermediate routes, particularly once the field opens up away from any blitz Spagnuolo runs. Philadelphia has multiple avenues to victory, whether through ground control or explosive plays, while Kansas City’s diminished explosiveness and early-season inconsistencies make it difficult to trust them to finish drives. With the Eagles’ balance, depth, and proven ability to exploit weaknesses, this spread is small enough to grab some value.

Prediction

This game will carry all the theater that was missing in February’s one-sided Super Bowl, and both teams will be determined to control the narrative. Kansas City will lean on Mahomes’ improvisational magic, pairing quick throws to Brown and Kelce with Pacheco’s bruising runs to test Philadelphia’s linebacker group. At times, that approach will work, and Arrowhead’s energy could swing momentum in spurts. But the Eagles’ balance and physicality give them the edge when the game tightens late. Hurts has developed into the kind of quarterback who thrives in these national spotlight moments, and Barkley’s presence behind one of football’s best offensive lines allows Philadelphia to wear down defenses when it matters most. The Eagles’ defensive front has the ability to collapse pockets and force Mahomes into hurried decisions, creating turnovers or stalled drives. With Quinyon Mitchell and Cooper DeJean providing fresh legs and speed to the secondary, Kansas City’s receivers will be challenged all evening. When the final minutes arrive, Philadelphia’s depth and discipline should tilt the scale, just as it did throughout last season’s playoff run. This won’t be a blowout, and the Chiefs will show flashes of their old dominance, but the Eagles are better equipped to land the final punches in a hard-fought battle to solidify their status as the favorite to claim back-to-back Super Bowls in February.

Final Score: Eagles 23, Chiefs 17

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Falcons @ Vikings (-1.5) (O/U: 42.5)

U.S. Bank Stadium, Minneapolis, MN

8:20 pm, NBC/Peacock

For the second time since leaving the Vikings, Kirk Cousins makes his return back to a place he called home for six seasons, but this time, he won’t be starting for the Falcons, as Michael Penix Jr. looks to get revenge on JJ McCarthy following their battle in the CFP National Championship two seasons ago. That storyline alone would be enough to draw eyes, yet Sunday night offers far more than nostalgia and college football flashbacks, as two franchises at vastly different points in their quarterback timelines meet in a spotlight game that could define the tone of their Septembers. Penix enters off a promising but painful debut, where he filled the box score but fell just short against Tampa Bay, and now he walks into one of the NFL’s most hostile environments with a chance to deliver a signature win that would cement Atlanta’s standing as a true contender. McCarthy, meanwhile, comes in fresh off a rollercoaster debut in Chicago, where his late surge reminded fans why the Vikings hitched their future to his arm despite the missed time in 2024. With Penix eager to validate his promise, McCarthy searching for consistency, and stars like Robinson and Jefferson looking to make even bigger impacts this time around, this primetime clash will certainly hold an intrigue that will reveal a lot more about how competitive the NFC as a whole could be.

Best Bet: Over 42.5

I think this matchup has all the makings of a game where the total doesn’t just creep past the line but sails over it, because while both defenses have intriguing young pieces that could become difference-makers later in the season, neither unit looks fully ready to keep pace with the firepower they’re about to face on Sunday night. Penix wasted no time showing he can stretch the field vertically, and with Robinson capable of creating havoc both between the tackles and in open space, Drake London and a finally healthy Darnell Mooney both emerging as reliable targets on the outside, and Kyle Pitts Sr. finally being utilized as a true mismatch piece, Atlanta has the weapons to stress the Vikings on every level of its defense. Minnesota, however, showed in Week 1 that their own offense can be just as punishing, as Jefferson looked in midseason form immediately and reestablished his connection with McCarthy in clutch moments, while Aaron Jones Sr. brought balance and reminded defenses that he still has the versatility to punish mismatches out of the backfield. Both teams flashed explosiveness in their openers, both secondaries struggled to close out games, and both quarterbacks are unafraid to take shots downfield, which creates the kind of back-and-forth rhythm that feeds a shootout. With momentum swings likely dictated by star playmakers rather than defensive stops, I fully expect this contest to clear the projected total with room to spare.

Prediction

Like I mentioned before, this game is ultimately going to come down to which offensive skill players can consistently make the biggest plays, and while the margin feels razor-thin, the slight edge leans toward Minnesota. Penix is going to have his moments, especially with Robinson capable of turning even the most routine touches into highlight plays that swing momentum, but the way this offense will lean on several stars like Jefferson, Thielen, and Hockenson through the air as well as Jones and Mason on the ground will give the Vikings a stabilizing force that is difficult to match. Atlanta’s defensive front, anchored by a young core that continues to grow, will certainly look to pressure McCarthy into rushed throws and capitalize on any rookie mistakes, yet Minnesota’s offensive line appears equipped to give him just enough time to stay in rhythm and make the calculated throws that can separate tight games. This doesn’t feel like the type of matchup that will be decided by field goals or conservative coaching decisions, but rather by which young quarterback embraces the moment and delivers the gutsier throws in crunch time, and which defense manages to find that one defining stop in a contest tilted toward offense. Add in the boost of a home opener and the energy of a crowd eager to usher in a new era, and it feels like the Vikings will find the extra push they need to grind out a victory and move to 2-0 on Sunday night.

Final Score: Vikings 30, Falcons 28

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Monday, September 15

Buccaneers @ Texans (-2.5) (O/U: 42.5)

NRG Stadium, Houston, TX

7 pm, ABC/ESPN

The first of Monday’s doubleheader brings a spotlight matchup in Houston, where the Texans host the Buccaneers in a game that not only showcases star power on both sides of the ball but also highlights two franchises with lofty expectations and very different questions that demand immediate answers. For Tampa Bay, the season began with a hard-fought divisional win in Atlanta, a contest in which Baker Mayfield leaned heavily on the deep threat reliability of Mike Evans and the promise of rookie Emeka Egbuka to manufacture just enough offensive production, while a retooled defense tightened late to preserve the victory. Yet even in that moment of success, the Bucs were reminded of their vulnerabilities, as the absences of Chris Godwin and Tristan Wirfs leave Mayfield behind a patchwork offensive line, forcing both him and the coaching staff to improvise under pressure against one of the league’s fiercest defensive fronts. Houston, meanwhile, enters the night looking to shake off a frustrating opener against the Rams, where CJ Stroud was hurried throughout the evening, preventing the Texans from unlocking the vertical passing game that made them such a dangerous team a year ago. Still, the roster remains more complete, boasting a fast, disruptive defense and an arsenal of offensive weapons that should eventually overwhelm, making this contest feel less like a routine early-season checkpoint and more like an immediate measure of which contender has the foundation to endure.

Best Bet: Texans -2.5

Is Houston’s sluggish offensive outing in Los Angeles cause for concern? In some respects, yes, but there is far more reason to believe the Texans will sort out their issues than to expect Tampa Bay to suddenly solidify its defensive shortcomings, particularly against the pass. With Joe Mixon sidelined for several weeks and Nick Chubb still regaining rhythm after a long recovery, Houston will continue leaning heavily on Stroud’s arm, a formula that should favor them given Tampa Bay’s secondary vulnerabilities. Nico Collins, who was quiet in the opener, seems poised for a bounce-back night, especially with Stroud’s proven ability to recover quickly from subpar performances and the emergence of new receiving options demanding attention from defenses. The Buccaneers, by contrast, remain dependent on Mayfield’s improvisation and Evans’s reliability to mask an offense that is still uneven, with their ground game sputtering and the protection unit weakened by Wirfs’s absence. Even their Week 1 win required late-game heroics, hardly a sustainable model against a Houston defense that thrives on disrupting rhythm and dictating tempo. Considering the matchup dynamics and Houston’s potential to establish momentum early through the air, the Texans are well-positioned to seize control and cover by at least a field goal.

Prediction

This game has the potential to produce more scoring bursts than some might expect, yet Houston’s defensive speed and discipline combined with the Buccaneers’ lingering injuries suggest the decisive swings will lean heavily toward the home team. Stroud’s ability to operate off play action behind a fortified offensive line should create just enough windows to exploit Tampa Bay’s coverage mismatches, particularly against a secondary that has struggled to consistently handle layered route combinations while defenders are forced to respect the run. Mayfield will generate occasional sparks through veteran targets like longtime veteran Evans and the rapidly emerging Egbuka, but sustaining drives against Houston’s front remains a monumental task, as both Will Anderson Jr. and Danielle Hunter possess the power and speed to collapse pockets and disrupt timing, while the linebacker and secondary units funnel plays into tight windows designed to force errors. On offense, Houston doesn’t require explosive plays to dominate; instead, Stroud only needs consistent execution, methodically distributing the ball to his weapons and forcing the Buccaneers to extend coverage rotations until small lapses create opportunities. As the game wears on, injuries and depth limitations on the Bucs’ side should compound, allowing Houston to seize critical momentum and dictate the closing stages, a dynamic that makes the home team well-positioned to emerge victorious when it truly matters.

Final Score: Texans 28, Buccaneers 23

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Chargers (-3.5) @ Raiders (O/U: 46.5)

Allegiant Stadium, Las Vegas, NV

10 pm, ESPN

The other half of Monday’s doubleheader features a divisional matchup in Las Vegas when an old Pac-12 and NFC West coaching rivalry makes a return as Jim Harbaugh’s Chargers visit Pete Carroll’s Raiders. Los Angeles comes into this game riding the high of a thrilling Week 1 victory in São Paulo, having shown both the potential and precision of a squad now fully shaped in Harbaugh’s image, but the question remains whether they can replicate that balance against a Raiders team coming off an encouraging home opener. Justin Herbert, fresh off a 318-yard, three-touchdown performance, will once again be the centerpiece of an offense that leans heavily on a power run game to complement its aerial attack, with Najee Harris and Omarion Hampton expected to provide the physicality and downhill momentum that Greg Roman’s system demands. On the perimeter, Keenan Allen and Quinten Johnston have already demonstrated chemistry and big-play ability, while second-year breakout candidates like Ladd McConkey offer the speed to stretch the field in space and create lanes for Herbert to exploit. Meanwhile, Los Angeles’ defense, led by Khalil Mack and Derwin James Jr., has the speed and discipline to pressure Geno Smith and disrupt timing routes, but with a new-look interior and rookies rotating, they must remain cohesive to prevent explosive plays. The stage is set for a matchup where coaching adjustments, in-game adaptability, and execution under pressure will determine which squad asserts early control in this pivotal AFC West duel.

Best Bet: Brock Bowers o51.5 Receiving Yards

Brock Bowers’ second season in Las Vegas has already shown signs of becoming a breakout campaign, and with Geno Smith at quarterback under a refined system led by Chip Kelly and Pete Carroll, the Raiders’ passing attack has never looked more dynamic. Bowers has quickly emerged as the focal point of an aerial scheme built to exploit mismatches and stretch defenses, and tonight’s matchup presents the perfect opportunity for him to thrive against a Chargers front that is still settling into its rotations. With Jakobi Meyers and Tre Tucker drawing coverage across the field, Bowers will have room to operate in the middle and over the top, using his size, athleticism, and refined route-running to create separation and maximize yardage. The Raiders’ commitment to a faster-paced, spacing-focused offense means Smith will rely heavily on his tight end in critical short-to-intermediate situations, particularly on third downs and in the red zone, funneling targets to the player who can consistently move chains and generate explosive plays. Ashton Jeanty will help maintain balance and control the clock, but the true volume of targets and yardage is poised to flow through Bowers, who now possesses the skill set, opportunity, and supporting cast to hit the over on his receiving yard prop and solidify himself as one of the league’s most dangerous second-year tight ends.

Prediction

The defensive pressure that both of these teams will bring on Monday Night Football will be very strong, but I’m expecting about the same amount of scoring as their January meeting last season. The Raiders’ front, anchored by Maxx Crosby and bolstered by a revitalized interior, has the athleticism and depth to challenge Justin Herbert and disrupt timing between quarterback and receivers, but Los Angeles’ offensive line provides the experience and stability necessary to give Herbert the time to dissect coverage and find open targets downfield. On the other side, Geno will be asked to maintain rhythm while avoiding pressure from the Chargers’ defensive front, which can rotate edge rushers to keep constant heat on the quarterback while also spying the run game effectively. Najee Harris and Omarion Hampton remain pivotal to sustaining drives and keeping the Raiders’ defense honest, and the matchup in the trenches will likely dictate which team controls possession and tempo. Carroll and Harbaugh bring their typical intensity and willingness to make adjustments on the fly, and the result should be a game where every big play, third-down conversion, and turnover carries heightened significance. Jim Harbaugh gets the best of Pete Carroll this time, and the Chargers get another key divisional win to move to 2-0 on the year.

Final Score: Chargers 31, Raiders 20

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Make sure to stay tuned this weekend as we learn a little more about some of the top teams in a stacked Week 2 slate to kick things off for the 2025-26 NFL season!